This book applies Augustine's thought to current questions of teaching and learning. The essays are written in an accessible style and is not intended just for experts on Augustine or church history.

Nancey Murphy has been influential in the religion‐and‐science field through her espousal of the work of Imre Lakatos, more recently developed into a three‐tier approach to the joint epistemology of scientific and religious thought incorporating also the ideas of Hempel and MacIntyre. She has proposed a substantial influence of the radical reformed tradition on science and has demonstrated the nature of social influences on the form of Darwinism. She has developed important links between ethics and the science‐theology debate and (...) has examined in depth ideas associated with hierarchical structuring, supervenience, and the nature of the soul. Together these form a unique and sharply focused contribution to the understanding of the relation between science and religion. (shrink)

Flesh of My Flesh is a collection of articles by today's most respected scientists, philosophers, bioethicists, theologians, and law professors about whether we should allow human cloning. It includes historical pieces to provide background for the current debate. Religious, philosophical, and legal points of view are all represented.

In a provocative essay, philosopher Jeffrie G. Murphy asks: 'what would law be like if we organized it around the value of Christian love, and if we thought about and criticized law in terms of that value?'. This book brings together leading scholars from a variety of disciplines to address that question. Scholars have given surprisingly little attention to assessing how the central Christian ethical category of love - agape - might impact the way we understand law. This book (...) aims to fill that gap by investigating the relationship between agape and law in Scripture, theology, and jurisprudence, as well as applying these insights to contemporary debates in criminal law, tort law, elder law, immigration law, corporate law, intellectual property, and international relations. At a time when the discourse between Christian and other world views is more likely to be filled with hate than love, the implications of agape for law are crucial. (shrink)

The book includes contributions by Sarah-Jayne Blakemore, George F. R. Ellis, Christopher D. Frith, Mark Hallett, David Hodgson, Owen D. Jones, Alicia Juarrero, J. A. Scott Kelso, Christof Koch, Hans Küng, Hakwan C. Lau, Dean Mobbs,...

Woods et al. (2015) claim that secular Simple Reaction Time (SRT) slowing (Woodley et al. 2013), disappears once modern studies are corrected for software and hardware lag, and once Galton’s data are corrected for fastest-response selection. Here, this is challenged with a reanalysis of the secular slowing of SRT in the UK amongst large (N>500), population-representative age-matched (≊18-30 years) studies. Starting with Galton’s sample, this is assigned the simulated value estimated by Dodonova and Dodonov (2013, who like Woods et al. (...) were critical of secular SRT slowing, owing to measurement issues) on the basis that he collected the fastest of three trials (207.5ms). The two sexes in Galton’s study are combined (as in Woods et al.), raising the weighted sample mean to 208.5ms. Next is the Wilkinson and Alison (1989) study, which attempted to replicate Galton’s study one century later, collecting SRTs as part of an exhibit in the London Science Museum. An electronic chronoscope recorded SRTs on magnetic tape, and sampled over eight trials with micro-processor-determined variable foreperiods. The mean SRT value for the 1,189 participants aged between 20 and 29 is 245ms. The presence of long and variable foreperiods necessitates a penalty of 10ms (Dodonova & Dodonov, 2013). Another 10ms should be deducted based on key-pressing time (Dodonova & Dodonov, 2013), reducing the mean to 225ms. The studies of Deary and Der (2005) and Der and Deary (2006) are also included. The first utilized the highly representative Scottish Twenty-07 cohort. Dodonova and Dodonov (2013) identified a 53ms lag stemming from liquid crystal stimulus onset delay. This is subtracted from the weighted average of the two sexes (300.8ms), along with another 10ms for key-pressing time. The resultant mean is 237.8ms.Dodonova and Dodonov (2013) cleaned the male data in the Der and Deary (2006) study, collected from the representative UK Health and Lifestyle Survey, by removing cases for which SRT standard deviations exceeded those for choice RT. This reduced the N from 834 to 661, and also reduced the mean from 300ms to 284ms. The estimate was also penalized for LCD onset delay and key-pressing time, reducing the mean to 221ms. When the SRT value for the female sample is penalized equivalently the resulting value is 239ms. In order to simulate the female N for the purposes of taking a weighted average of both sexes, the actual female N is reduced in proportion to the male N (79.3%=881), yielding a weighted mean of 230.9ms for a combined sample-size of 1,472. Table 1 presents the data used in the analysis.Table 1 SRT means, sample sizes and sampling years for four large, age-matched UK samples[Table 1 here]Consistent with Dodonova and Dodonov (2013), N-weighted regression is employed, as the only data on sample variability is sample size. Figure 1 illustrating the secular trend in UK SRT over 100 years.[Figure 1 here] Figure 1. Secular SRT slowing across four large, representative studies from the UK spanning a century. Bubble-size is proportional to sample size. Combined N=6,622. The secular slowing between UK studies is statistically significant (β=0.97; 95% CI=0.969 to 0.971, N=6,622), at –22.8ms a century. Additional evidence for generational SRT slowing comes from Verhaeghen (2014), who suggested that the ratio of longitudinal to cross-sectional age-related slowing might tentatively infer generational changes in processing speed. Verhaeghen reports ratios for two SRT studies (0.91 and 1.15), implying both secular losses and gains. For the study of Deary and Der (2005), the SRT ratios are “censored because they were excessively large” (p. 256). In this study, the ratio of the cross-sectional slowing trend (taking the weighted average of all paired between-cohort differences rescaled in terms of change per decade for males and females), to the weighted average decadal longitudinal slowing trend for both the males and females is 0.73, for an N of 1,926 (cf. Woodley et al., 2014b, for a detailed reanalysis of this dataset). The weighted average of the three SRT ‘Verhaeghen ratios’ is 0.9 (N=4,078) – tentatively consistent with generational declines (i.e. a ratio of <1). In conclusion Woods et al. (2015) have undoubtedly made an important contribution to the debate concerning the role of software and hardware lag in the inflation of contemporary estimates of SRT, however the evidence for generational SRT slowing remains quite compelling. ReferencesDeary, I.J., & Der, G. (2005). Reaction time, age, and cognitive ability: Longitudinal findings from age 16 to 63 years in representative population samples. Aging, Neuropsychology, and Cognition, 12, 187–213.Der, G., & Deary, I.J. (2006). Age and sex differences in reaction time in adulthood: Results from the United Kingdom Health Lifestyle Survey. Psychology and Aging, 21, 62–73.Dodonova, Y.A., & Dodonov, Y.S. (2013). Is there any evidence of historical slowing of reaction time? No, unless we compare apples and oranges. Intelligence, 41, 674–687.Galton, F. (1890). Exhibition of instruments (1) for testing the perception of differences of tint, and (2) for determining reaction-time. Journal of the Anthropological Institute, 19, 27–29.Verhaeghen, P. (2014). The elements of cognitive aging: Meta-analyses of age-related differences in processing speed and their consequences. Oxford: Oxford University Press.Wilkinson, R.T., & Allison, S. (1989). Age and simple reaction time: Decade differences for 5,324 subjects. Journal of Gerontology, 44, 29–35.Woodley, M.A., Madison, G., & Charlton, B.G. (2014b). Possible dysgenic trends insimple visual reaction time performance in the Scottish Twenty-07 cohort: Areanalysis of Deary & Der (2005). Mankind Quarterly, 55, 110-124.Woodley, M.A., te Nijenhuis, J., & Murphy, R. (2013). Were the Victorians cleverer than us? The decline in general intelligence estimated from a meta-analysis of the slowing of simple reaction time. Intelligence, 41, 843–850.Woods, D.L., Wyma, J.M., Yund, E.W., Herron, T.J., & Reed, B. (2015). Factors influencing the latency of simple reaction time. Frontiers in Human Neuroscience, 9:131. (shrink)

Plato. Crito.--Mill, J. S. Utilitarianism.--Rawls, J. Two concepts of rules.--Kant, I. Fundamental principles of the metaphysic of morals.--Rawls, J. Justice as fairness.--Benn, S. I. and Peters, R. S. Society and types of social regulation.--Hobbes, T. Leviathan, abridged.--Hayek, F. A. The principles of a liberal social order.--Marx, K. Alienation and its overcoming in Communism.--Lukes, S. Alienation and anomie.--Garver, N. What violence is.--Zinn, H. The force of nonviolence.--Caudwell, C. Pacifism and violence; a study in bourgeois ethics.--Bennett, J. Whatever the consequences.--Foot, P. Abortion (...) and the doctrine of the double effect.--Benn, S. I. Punishment.--Mill, J. S. Selection from On liberty.--Mill, J. S. Selection from Considerations on representative government.--Marcuse, H. The new forms of control.--Mill, J. S. The subjection of women, abridged.--Dickinson, J. A working theory of sovereignty, abridged.--Rawls, J. The justification of civil disobedience. (shrink)

Reply to a commentary by Timothy F. Murphy.

R F Dearden; Play and Pleasure, Journal of Philosophy of Education, Volume 5, Issue 1, 30 May 2006, Pages 37–41, https://doi.org/10.1111/j.1467-9752.1971.tb0044.

R. F. Atkinson; XIII*—Explanation in History, Proceedings of the Aristotelian Society, Volume 72, Issue 1, 1 June 1972, Pages 241–256, https://doi.org/10.1093/a.

The metics of Gortyna came under the jurisdiction of the special courts for foreigners, κσενεία δίκα, and of the κσένιος κόσμος, an official who is often named in Gortynian inscriptions. From one of these we can infer that freedmen were classed with metics, because of the artisan status of both.

The amplitude and the diversity of Ricoeur’s philosophical production is astonishing. Three factors shed light upon this fact. First, his philosophical career covers seventy years wherein he witnessed the rise and the decline of tlve philosophical -isms. Further, he is a typical dialogical thinker: in conversation with the great classical and modern philosophers, and eager to listen to the methods and results of human an linguistics sciences. A third reason, particularly of differentiation, stems from his double conviction and commitment. On (...) the one hand, he wants to be a rigorous philosopher, even keeping on a methodic agnosticism. On the other hand, however, he is a convinced Christian, and so he also likes to think critically – a rigorous philosophizing here is inappropriate – on religion, belief, and biblical language and topics. Nevertheless, it is only since 2000 that he is getting fully aware of the disintegrated impression many readers have from his publications. In his opinion, this impression is perfectly understandable: a reading public and myself are on completely different wavelengths. From reading my books people spontaneously nurture their own expectation with regard to coming publications, whereas my concern always was: am I answering your questions? So, in four recent articles Ricoeur speaks of his technical philosophy composed of eleven books: from The voluntary and the Involontary to the Course of Recognition . He argues that the continuity of his basic philosophical writings is, each time, determined by a residue, a question the preceding publication left open. But, where to situate then his twenty-two other books into a global and consistent picture? All these other works are explorations of specific philosophical issues, and reflections and topics as prophecy, tragedy and religion bordering philosophy. For this matter, a fully rigorous philosophical discourse is not always possible. These writings, however, find their setting around the hard core of his philosophy. Ricoeur himself only mentions two genres: volumes of articles for a larger audience as History and Truth and university lectures as Lectures on Ideology and Utopia . But other headings need to be added to umbrella other publications: historical and autobiographic writings, collection of articles on political topics, on the sacred and biblical language, on philosophy of law, and on medical ethical issues. On a more remote distance from the heart of his philosophy are located hundred of articles and interviews on philosophical topics, reflections on actual themes, an even some homilies. To amazement of many, two eminent Ricoeur commentators recently characterized his philosophy as “An Ontology of Life”. This is not as strange as it looks! Already in The voluntary and the Involontary. Ricoeur offers a phenomenology of “life, to be in life and birth”. To him, life also is a lived and hard-won value. In fact, belief in life is related to his main category of “originative affirmation” and of “hope”. Hope, however, is never a knowledge but only the regulative idea of my metaphysical thinking, and it remains inextricably bound up with the anguish for a senseless totality. “Nothing is closer to the anguish of nonsense than timid hope.”. (shrink)

The following is a report of a meeting of the British Society for Cell Biology on ‘The Cell Cycle’, at St Andrews University, 4‐6 April, 1989.

Positive transcription elongation factor b (P‐TEFb), which comprises cyclin‐dependent kinase 9 (CDK9) kinase and cyclin T subunits, is an essential kinase complex in human cells. Phosphorylation of the negative elongation factors by P‐TEFb is required for productive elongation of transcription of protein‐coding genes by RNA polymerase II (pol II). In addition, P‐TEFb‐mediated phosphorylation of the carboxyl‐terminal domain (CTD) of the largest subunit of pol II mediates the recruitment of transcription and RNA processing factors during the transcription cycle. CDK9 also phosphorylates (...) p53, a tumor suppressor that plays a central role in cellular responses to a range of stress factors. Many viral factors affect transcription by recruiting or modulating the activity of CDK9. In this review, we will focus on how the function of CDK9 is regulated by viral gene products. The central role of CDK9 in viral life cycles suggests that drugs targeting the interaction between viral products and P‐TEFb could be effective anti‐viral agents. (shrink)